Toxic thyroid nodules are best treated with radioactive iodine as this concentrates on the overactive adenoma cells. Radioiodine treatment is contraindicated in young children, pregnant and lactating women. The major complication of treatment with radioactive iodine is the progressive incidence of hypothyroidism and thyroid replacement may be necessary in the future.

The appropriate initial treatment of Amiodarone induced hyperthyroidism would be carbimazole +/- steroids