Friday 25 August 2017

The features of X linked inheritance are:



Males are all affected
Females only occasionally show mild signs of disease
Each son of a carrier a 1:2 chance of being affected
Each daughter of a carrier has a 1:2 risk of being a carrier
Daughters of affected males will all be carriers
Sons of affected males will be affected

X linked dominant (rare)
X linked Hypophosphataemic rickets von Willebrand's disease

X linked recessive
Becker’s muscular dystrophy Duchenne’s muscular dystrophy Fabry’s disease
Hunter’s syndrome
Glucose 6 Phosphate denydrogenase deficiency red-green colour blindness
haemophilia A and B
Testicular feminisation syndrome
Wiskott Aldrich syndrome

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