Barbiturate withdrawal in an habitual abuser a well recognised cause of fits. Benzodiazepine elevates the
level of an inhibitory
neurotransmitter, GABA, therefore
it serves as a tranquilizer. Barbiturates
are prescribed as anticonvulsants, sedatives, and general anesthetics.
Commonly abused barbiturates include amobarbital
(Amytal),
pentobarbital (Nembutal), and secobarbital (Seconal). These drugs depress the respiratory
and nervous system functions. Symptoms of withdrawal syndrome appear
12-20 hours after the last dose; they include anxiety, irritability, elevated heart
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