Barbiturate withdrawal in an habitual abuser a well recognised cause of fits. Benzodiazepine elevates the level of an inhibitory neurotransmitter, GABA, therefore it serves as a tranquilizer. Barbiturates are prescribed as anticonvulsants, sedatives, and general anesthetics. Commonly abused barbiturates include amobarbital

(Amytal), pentobarbital (Nembutal), and secobarbital (Seconal). These drugs depress the respiratory and nervous system functions. Symptoms of withdrawal syndrome appear 12-20 hours after the last dose; they include anxiety, irritability, elevated heart