Clozapine induced agranulocytosis occurs in about 1% to 10% of patient who take clozapine. Patients who have experienced agranulocytosis with prior treatment of clozapine should not receive clozapine again.

Hyperkalaemia, hirsutism, tremors, hypertension, nausea and vomiting, headache, gum hypertrophy, parasthesiae and hypomagnesaemia are side effects of ciclosporin.