The HACEK organisms are:
Haemophilus
species (H. aphrophilus, H. paraphrophilus, H. parainfluenzae) Actinobacillus actinomycetemcomitans
Cardiobacterium hominis
Eikenella corrodens
Kingella
These are gram
negative bacilli which are responsible for 5-10% of cases of infective endocarditis (IE) involving native
valves and are the most common
cause of gram-
negative endocarditis among persons who
do not abuse intravenous drugs.
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